Anthrax attacked!

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Anthrax.

Anthrax is an often fatal bacterial infection that occurs when Bacillus anthracis endospores enter the body through one of three major routes: inhalational, cutaneous, or gastrointestinal. Before the anthrax terrorist attacks in the United States in 2001, there was very little interest in anthrax as a serious human pathogen; anthrax was viewed mainly as a veterinarian problem of minor importanc...

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[Anthrax].

Having dwelled on the etiopathogenetic, pathologic, and clinical features of human infections caused by B. anthracis, the authors review and analyze epidemiological data of the cases of anthrax registered in Italy during the last ten years. Actual possibilities for prevention are evaluated in view of the fact that enzootic foci still exist in our country which are clearly responsible for the ty...

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Anthrax: A motor protein determines anthrax susceptibility

A new study has found that polymorphisms in the host gene kif1C, which encodes a kinesin-like motor protein, determine whether mouse macrophages are resistant or sensitive to anthrax lethal toxin. These findings may lead the way to discovering how both germ and host factors might contribute to a lethal infection.

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Selecting Countermeasures for ICT Systems Before They are Attacked

A countermeasure is any change to a system to reduce the probability it is successfully attacked. We propose a model based approach that selects countermeasures through multiple simulations of the behaviors of an ICT system and of intelligent attackers that implement sequences of attacks. The simulations return information on the attacker sequences and the goals they reach we use to compute the...

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ژورنال

عنوان ژورنال: Nature Reviews Drug Discovery

سال: 2004

ISSN: 1474-1776,1474-1784

DOI: 10.1038/nrd1291